SS-31

Mitochondria-targeting tetrapeptide (elamipretide) that stabilises cardiolipin.

SS-31 (also known as elamipretide) is a mitochondria-targeting tetrapeptide that has been extensively studied for its ability to support mitochondrial function and reduce oxidative stress. Research suggests that SS-31 selectively binds to cardiolipin within the inner mitochondrial membrane, helping to stabilize mitochondrial structure, improve electron transport chain efficiency, enhance ATP production, and reduce the formation of reactive oxygen species (ROS). In preclinical models, these effects have been associated with improved cellular energy metabolism, reduced inflammation, protection against ischemia-reperfusion injury, and preservation of tissue function in the heart, skeletal muscle, kidneys, brain, and eyes. Early clinical trials have also demonstrated a favorable safety profile and have investigated SS-31 for conditions involving mitochondrial dysfunction, including primary mitochondrial diseases, heart failure, age-related disorders, and rare genetic conditions, although efficacy has varied depending on the indication studied. Overall, the available evidence suggests that SS-31 has significant potential as a mitochondria-protective peptide.

Elamipretide · 50mg · For laboratory and research use only. Not for human or animal consumption. 18+ qualified researchers only.